PROTAC EGFR degrader 4, CAS [[2882845-50-1]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T74515
Supplier Catalog Number:
T74515
Alternative Catalog Number:
TGM-T74515-5MG,TGM-T74515-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
PROTAC EGFR degrader 4 is a potent molecule designed to target and degrade mutant EGFR, effectively inducing degradation of EGFR del19 and EGFR L858R/T790M with DC50 values of 0.51 nM and 126 nM, respectively. It significantly inhibits the growth of HCC827 and H1975 cell lines, demonstrating IC50 values of 0.83 nM and 203.1 nM, respectively. The induced degradation of EGFR by this compound is associated with autophagy [1].
Molecular Weight:
995.29
CAS Number:
[2882845-50-1]
Formula:
C55H70N12O4S
Target:
Others|||PROTACs|||Autophagy|||EGFR
T74515
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