RNA polymerase II-IN-2 (compound 20iii), a potent inhibitor of RNA polymerase II (Pol II) with a K i value of 9.5 nM, exhibits cytotoxicity against cancer cells, demonstrating toxicity levels 2 and 5 times higher than alpha-amanitin in CHO and HEK293 cells, respectively [1].
Molecular Weight:
915.02
Formula:
C41H58N10O12S
Target:
DNA/RNA Synthesis|||Others
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