Eplontersen is a triantennary N-acetylgalactosamine-conjugated antisense oligonucleotide that selectively inhibits both wild-type and mutant transthyretin mRNA, thereby reducing pathogenic TTR protein production and amyloid fibril formation associated with ATTR amyloidosis affecting cardiac and peripheral nerve tissues.
Molecular Weight:
8606.5
CAS Number:
[1637600-16-8]
Target:
Others
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