Setidegrasib (example 8), a quinazoline-linked (4R)-4-hydroxy-L-prolinamide compound, acts as a proteolysis targeting chimera (PROTAC) [1], specifically inducing degradation of the G12D-mutation KRAS protein.
Molecular Weight:
1117.3
CAS Number:
[2821793-99-9]
Formula:
C60H65FN12O7S
Target:
Others|||Kras|||PROTACs|||Ras
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