TUS-007, a modified CANDDY (Chemical knockdown with Affinity aNd Degradation DYnamics) molecule originally derived from a proteasome inhibitor, scarcely affects proteasome activity. It is a potent, orally active degrader of KRAS G12D/V, effective in cell-free chemical knockdown of KRAS G12D/V. Furthermore, TUS-007 has been shown to suppress tumor growth [1].
Molecular Weight:
845.86
CAS Number:
[2227029-18-5]
Formula:
C44H54Cl2N8O5
Target:
Others|||Kras|||Ras
T74755
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