YL5084, a covalent inhibitor selective for JNK2 and JNK3 over JNK1, demonstrates IC50 values of 70 nM and 84 nM for JNK2 and JNK3, respectively, compared to 2173 nM for JNK1. This compound also shows antiproliferative effects and induces apoptosis independently of JNK2 activity [1].
Molecular Weight:
600.71
CAS Number:
[2440199-73-3]
Formula:
C35H36N8O2
Target:
Others|||Apoptosis|||JNK
T74850
* VAT and and shipping costs not included. Errors and price changes excepted
