JZP-MA-11 is a positron emission tomography (PET) ligand that specifically targets the endocannabinoid alpha/beta-hydrolase domain 6 (ABHD6) enzyme. It exhibits selective inhibition of ABHD6 with an IC50 value of 126 nM and can cross the blood-brain barrier (BBB). The compound, labeled with [18F], shows promising potential for preclinical evaluation in mice and nonhuman primates (NHP) as a tool for investigating brain ABHD6 activity [1].
Molecular Weight:
336.38
CAS Number:
[1672691-50-7]
Formula:
C15H17FN4O2S
Target:
Others|||MAGL
T75022
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