STING agonist-23 (CF508), a non-nucleotide small-molecule STING agonist, activates STING, thereby enhancing the phosphorylation of STING, TBK1, and IRF3. This activation elevates the production of IFN-beta, IL-6, CXCL-10, TNF-alpha, ISG-15, and CCL-5 in tumor cells. Moreover, STING agonist-23 demonstrates efficacy against SARS-CoV series strains [1].
Molecular Weight:
819.91
CAS Number:
[2868261-48-5]
Formula:
C40H49N15O5
Target:
Others|||STING
T75094
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