Loxosceles Pilosa Venom, derived from Loxosceles Pilosa, comprises a sophisticated blend of proteins, glycoproteins, and low molecular mass peptides. This venom contains various protein classes such as astacin-like metalloprotease, insecticidal peptides of low molecular mass, inhibitor cysine knot peptides (ICK), and phospholipase-D. Notably, the enzyme sphingomyelinase D is pivotal for necrosis development [1].
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