Voxelotor (GBT 440) is a novel hemoglobin S (HbS) polymerization inhibitor primarily used for the treatment of sickle cell disease (SCD) and a cytochrome P450 3A4 inhibitor. Voxelotor targets and covalently binds to the N-terminal valine of the HbS alpha chain, thereby stabilizing sickle cell hemoglobin (HbS).
Molecular Weight:
337.37
Purity:
99.87%
CAS Number:
[1446321-46-5]
Formula:
C19H19N3O3
Target:
Others
T7581
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