Orphanin FQ(1-11) TFA, a fragment of orphanin FQ or nociceptin (OFQ/N), acts as a powerful NOP receptor (ORL-1, OP4) agonist with a K i of 55 nM. It lacks affinity for µ, delta, kappa1, and kappa3 receptors (K i >1000 nM), demonstrating specificity, and exhibits analgesic properties in CD-1 mice [1] [2].
Molecular Weight:
1212.23
Formula:
C51H76F3N15O16
Target:
Opioid Receptor
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