TAT-cyclo-CLLFVY TFA is a cyclic peptide inhibitor targeting HIF-1 heterodimerization to mitigate hypoxia signaling within cancer cells. It effectively disrupts the protein-protein interaction between HIF-1alpha and HIF-1beta, with an inhibitory concentration (IC 50) of 1.3 µM [1].
Molecular Weight:
2673.1
Formula:
C113H189F3N42O26S2
Target:
HIF/HIF Prolyl-Hydroxylase
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