p3Ysh-3, a peptide inhibitor targeting the STEP Phosphatase-GluA2 AMPA receptor interaction, exhibits a Ki of 1.09 µM. It effectively reverses memory deficits and demonstrates anxiolytic and antidepressant effects in scopolamine-treated rat models, positioning itself as a promising lead compound for the development of novel cognitive enhancers and behavioral modulators [1].
Molecular Weight:
997.94
Formula:
C41H60N9O18P
Target:
iGluR
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