NoxaBH3, a cysteine-based cross-linked peptide, exhibits enhanced cell permeability and greater inhibitory efficacy against Mcl-1. It binds to the endogenous CXCR4 ligand, resulting in the formation of a ubiquitin-NoxaBH3 conjugate that is subsequently delivered to cancer cells [1].
Molecular Weight:
2156.68
Formula:
C90H162N32O25S2
Target:
CXCR
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