Simlukafusp alfa (FAP-IL2v) is a tumor-targeting immunocytokine and a human antibody with antitumor activity and immunostimulatory properties. It enhances the in vitro and in vivo activity of therapeutic antibodies that mediate antibody-dependent or T-cell-dependent cytotoxicity (TDCC) and inhibit the programmed death-ligand 1 (PD-L1) checkpoint. Simlukafusp alfa is intended for use in the study of solid tumors and the tumor immune microenvironment.
Purity:
94.30%
CAS Number:
[1776942-10-9]
Target:
Interleukin
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