Crovalimab, CAS [[1917321-26-6]]

Product Overview

• Article Name: Crovalimab, CAS [[1917321-26-6]]
• Biozol Catalog Number: TGM-T77190
• Supplier Catalog Number: T77190
• Alternative Catalog Number: TGM-T77190-1MG,TGM-T77190-5MG,TGM-T77190-10MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: SKY59 , SKY 59 , RO7112689 , RO 7112689

Product Description

Crovalimab (SKY59, RO7112689) is an Fc-engineered and pH-dependent humanised monoclonal antibody that binds to complement C5 and blocks its cleavage into C5a and C5b, thereby inhibiting MAC formation and intravascular haemolysis. It can rebind to the FcRn receptor under acidic pH conditions and return to the bloodstream, making it suitable for the treatment of paroxysmal nocturnal haemoglobinuria (PNH).

Product Properties

• Purity: 95%
• CAS Number: [1917321-26-6]
• Target: Complement System