GSK-3 inhibitor 4 is an orally active and brain-permeable compound that acts as a triple inhibitor of GSK-3, CDK2, and CDK5, with IC50 values of 0.56 nM (GSK-3beta), 0.45 nM (GSK-3alpha), 0.47 µM (CDK2), and 0.68 µM (CDK5). It effectively reduces Tau protein levels and can be used in the study of Alzheimers disease.
Molecular Weight:
403.38
Purity:
99.82%
CAS Number:
[2227279-83-4]
Formula:
C22H15F2N5O
Target:
CDK|||GSK-3
T77341
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