P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow. P-gb-IN-1 has been shown to inhibit P-gp by hydrogen bonding with residues Asn 721 and Met 986. P-gb-IN-1 showed low toxicity in MCF-7/ADR cells.
Molecular Weight:
512.55
Purity:
99.85%
CAS Number:
[2632874-49-6]
Formula:
C30H28N2O6
Target:
P-gp
T77575
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