TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the release of IL-1beta from the NLRP3 inflammasome (IC50: 5 µM) by inhibiting IL-1beta release from ATP-stimulated J1A.774 cells.
Molecular Weight:
267.24
Purity:
0.984
CAS Number:
[4765-59-7]
Formula:
C14H9N3O3
Target:
Wnt/beta-catenin|||PARP|||Antibiotic
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