SC239 is a 2-aminophenyl hemiasterlin-based agent-linker suitable for antibody-drug conjugate (ADC) applications. It features a tubulin-targeting warhead, SC209, connected through a cleavable valine-citrulline p-aminobenzyl carbamate linker equipped with dibenzocyclooctyne (DBCO). This drug-linker displays enhanced cytotoxic activity in Igrov1 cells with lower FolRalpha expression levels.
Molecular Weight:
1181.42
CAS Number:
[1977557-97-3]
Formula:
C65H84N10O11
Target:
Drug-Linker Conjugates for ADC
T77864
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