PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through inhibiting Eg5 ATPase activity. It binds to the alpha4/alpha6 allosteric pocket and demonstrates ATP-competitive activity [1].
Molecular Weight:
319.28
CAS Number:
[1141768-04-8]
Formula:
C13H9F4NO2S
Target:
Kinesin
T78125
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