6PPD-Q (6PPD-Quinone) is an environmental pollutant that can target CNR2, CNR1, AA2AR, LCAT and TRPA1. Among them, CNR2 has the highest binding affinity and may act as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q can damage the sperm quality and induce the impairment of male reproductive ability in mice. 6PPD-Q can induce intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolytic metabolites and TCA cycle intermediates, and exacerbating alpha-synuclein (alpha-syn) aggregation.
Molecular Weight:
298.38
Purity:
98.43%
CAS Number:
[2754428-18-5]
Formula:
C18H22N2O2
Target:
Endogenous Metabolite
T78474
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