Ethyl pivaloylacetate is a significant beta-ketoester. It is widely employed as a model substrate in biocatalysis to evaluate the catalytic activity and stereoselectivity of ketoreductase (KRED) tool-boxes. Due to the presence of the bulky pivaloyl (tert-butyl) group, it serves as an excellent probe for assessing the substrate pocket size and enantioselectivity of recombinant enzymes. The enzymatic reduction of this compound yields enantiopure beta-hydroxyesters, which are essential chiral building blocks for the synthesis of sophisticated pharmaceutical intermediates.
Molecular Weight:
172.22
Purity:
98.00%
CAS Number:
[17094-34-7]
Formula:
C9H16O3
Target:
Others
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