COX-2-IN-30, CAS [[1160498-08-7]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T78705
Supplier Catalog Number:
T78705
Alternative Catalog Number:
TGM-T78705-5MG,TGM-T78705-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2, IC50 = 49 nM) and cyclooxygenase-1 (COX-1, IC50 = 10.4 µM), as well as 5-lipoxygenase (5-LOX, IC50 = 2.4 µM). Additionally, it inhibits the transmembrane isoforms of human carbonic anhydrase IX and XII with nanomolar class Ki values. Demonstrating analgesic and anti-inflammatory properties, COX-2-IN-30 is devoid of acute gastric effects, avoiding ulcerogenic activity [1].
Molecular Weight:
384.41
CAS Number:
[1160498-08-7]
Formula:
C17H16N6O3S
Target:
Lipoxygenase|||COX|||Carbonic Anhydrase
T78705
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