JAK/HDAC-IN-2, a potent 2-amino-4-phenylaminopyrimidine dual-target inhibitor, effectively suppresses JAK1/2 and HDAC3/6 at nanomolar concentrations. This compound exhibits proapoptotic properties, inhibits histone deacetylation, and impedes STAT3 phosphorylation, demonstrating notable antiproliferative activity against various hematological malignancies and solid tumors [1].
Molecular Weight:
570.7
Formula:
C28H38N6O5S
Target:
Apoptosis|||JAK|||HDAC
* VAT and and shipping costs not included. Errors and price changes excepted
