NF-kappaB-IN-10 (compound E1) is an NF-kappaB inhibitor that mitigates heart failure symptoms by modulating the Nrf2/NF-kappaB signaling pathway, alleviating oxidative stress and inflammation. It suppresses LPS-induced NO production and downregulates iNOS and COX-2 expression in RAW264.7 cells, showing potential for cardiovascular disease research [1].
Molecular Weight:
434.53
Formula:
C26H30N2O4
Target:
NF-kappaB
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