JNK2-IN-1 (Compound J27), a selective JNK2 inhibitor with a dissociation constant (Kd) of 79.2 µM, exhibits anti-inflammatory effects by attenuating TNF-alpha and IL-6 secretion via inhibition of the NF-kappaB/MAPK pathway. It effectively mitigates symptoms associated with LPS-induced acute lung injury (ALI) and sepsis [1].
Molecular Weight:
522.55
Formula:
C30H26N4O5
Target:
JNK
* VAT and and shipping costs not included. Errors and price changes excepted
