CTL-06, a Fatty Acid Synthase (FASN) inhibitor with an IC50 of 3 µM, induces apoptosis, while CTL-12 impedes cell cycle progression in the Sub-G1/S phase and modulates apoptotic and anti-apoptotic markers by upregulating caspase-9 and Bax and downregulating Bcl-xL. Additionally, CTL-12 suppresses de novo lipogenesis, curtailing the metabolic needs of tumor cells, with utilization in breast and colorectal cancer studies [1].
Molecular Weight:
428.87
Formula:
C21H21ClN4O4
Target:
Others|||Fatty Acid Synthase
T78872
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