AMPA receptor modulator-6 (Compound 6) is a unique dimeric positive allosteric modulator that effectively stabilizes the dimer interface of AMPA receptors by physically bridging two adjacent ligand-binding domains. This structural anchoring significantly slows receptor desensitization and deactivation, thereby enhancing glutamate-mediated synaptic transmission.
Molecular Weight:
480.68
Purity:
99.96%
CAS Number:
[516491-33-1]
Formula:
C24H36N2O4S2
Target:
iGluR
T79504
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