WLB-89462 (Compound 20c) is a selective sigma2 receptor ligand with a K i of 13 nM, demonstrating neuroprotective properties and the capacity to ameliorate Abeta peptide-induced short-term memory impairment in rats. It exhibits a favorable ADMET profile, featuring good solubility, lack of CYP inhibition, strong metabolic stability, high permeability, effective brain penetration, and significant oral exposure in rodent models [1].
Molecular Weight:
399.49
CAS Number:
[2849471-75-4]
Formula:
C21H29N5O3
Target:
Sigma receptor
T79666
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