YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor (EGFR), with half-maximal inhibitory concentrations (IC50) of 0.96 nM for the wild-type EGFR and 0.67 nM for the L858R mutant variant. It induces G0/G1 cell cycle arrest and apoptosis in targeted cells [1].
Molecular Weight:
494.58
CAS Number:
[2470908-90-6]
Formula:
C30H30N4O3
Target:
Apoptosis|||EGFR
T80748
* VAT and and shipping costs not included. Errors and price changes excepted
