TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2). It effectively suppresses abnormal calcium (Ca 2+) waves and transients in isolated cardiomyocytes derived from mice with RyR2 mutations. As such, TMDJ-035 serves as a valuable tool in research for elucidating the gating mechanisms and dynamics of the RyR2 channel [1].
Molecular Weight:
347.29
CAS Number:
[2681302-83-8]
Formula:
C16H12F3N5O
Target:
Calcium Channel
T80975
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