SWELYYPLRANL-NH2 TFA acts as an antagonist to both E-cadherin and N-cadherin, with inhibitory effects on phage clone binding to E- or N-cad/Fc chimeric proteins, exhibiting IC50 values of 0.7 µM and 0.09 µM, respectively. Additionally, it disrupts cell aggregation and is utilized to enhance drug delivery by increasing the permeability of epithelial and endothelial barriers [1].
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