SR-29065 is a selective REV-ERBalpha agonist that inhibits BMAL1 transcription within the circadian transcription-translation feedback loop, and it has been applied to evaluate whether targeting both negative regulatory limbs of circadian control yields synergistic anti-tumor effects in glioblastoma models, supporting its broader use in autoimmune disorder and circadian rhythm research.
Molecular Weight:
518.52
Purity:
97.24%
CAS Number:
[2756883-91-5]
Formula:
C24H24F6N2O2S
Target:
Nuclear receptor
T81107
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