rTRD01 is a small-molecule TDP-43 ligand that binds the RRM1 and RRM2 domains of TDP-43 and partially disrupts its interaction with the pathogenic hexanucleotide RNA repeat of the c9orf72 gene, supporting the application of rTRD01 in mechanistic studies of RNA binding dysregulation in neurodegenerative disease research.
Molecular Weight:
344.38
Purity:
99.44%
CAS Number:
[1332175-56-0]
Formula:
C18H21FN4O2
Target:
Others
T81251
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