PH14, a dual PI3K/HDAC inhibitor, demonstrates potent inhibition with IC50 values of 20.3 nM for PI3Kalpha and 24.5 nM for HDAC3. It exhibits antiproliferative effects and induces apoptosis in Jeko-1 cells, making it a valuable tool in cancer research, including lymphoma studies [1].
Target:
PI3K|||HDAC|||Apoptosis
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