GW274150 dihydrochloride, CAS [[438542-17-7]] Preis auf Anfrage

Product Overview

• Article Name: GW274150 dihydrochloride, CAS [[438542-17-7]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T82251
• Supplier Catalog Number: T82251
• Alternative Catalog Number: TGM-T82251-5MG,TGM-T82251-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

GW274150 (dihydrochloride) is a potent and selective inhibitor of human and rat inducible nitric oxide synthase (iNOS), exhibiting oral activity and NADPH-dependence with an IC50 of 2.19 µM and Kd of 40 nM for human iNOS, and an ED50 of 1.15 µM for rat iNOS. It demonstrates reduced effectiveness against endothelial NOS (eNOS) and neuronal NOS (nNOS) in both species, and has shown protective effects in acute lung injury inflammation models [1] [2] [3].

Product Properties

• Molecular Weight: 292.23
• CAS Number: [438542-17-7]
• Formula: C8H19Cl2N3O2S
• Target: NO Synthase

Images

T82251