Columbamine chloride is an organic heterocyclic alkaloid and a metabolite of berberine which is widely found in Ranunculaceae plants such as Coptis and Phellodendron. Columbamine chloride induces apoptosis in cancer cells and exhibits anticancer activity. Columbamine chloride inhibits the cytochrome P450 (CYP) subtype CYP3A4 (IC50 = 30.6 µM). Columbamine chloride possesses various biological activities, including antioxidant, anti-inflammatory, antifungal, antiprotozoal, hepatoprotective, neuroprotective, lipid-lowering, and hypoglycemic effects.
Molecular Weight:
373.83
Purity:
99.79%
CAS Number:
[1916-10-5]
Formula:
C20H20ClNO4
Target:
Cytochromes P450|||Parasite|||Apoptosis
T82694
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