AC-099 (compound 3) serves as a selective full agonist at NPFF2R (EC50 = 1189 nM) and a partial agonist at NPFF1R (EC50 = 2370 nM). It has been shown to mitigate hypersensitivity induced by spinal nerve ligation in rats [1] [2].
Molecular Weight:
264.64
CAS Number:
[849459-88-7]
Formula:
C9H8ClF3N4
Target:
Neuropeptide FF Receptor|||Others
T83213
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