Mca-AVLQSGFR-K(Dnp)-K-NH2 serves as a fluorogenic substrate specifically designed for the main protease (Mpro) of the severe acute respiratory syndrome coronavirus (SARS-CoV), also referred to as 3C-like protease (3CLpro). This substrate, upon enzymatic cleavage by SARS-CoV Mpro, liberates 7-methoxycoumarin-4-acetyl (Mca) which emits fluorescence. This fluorescence emission, with excitation/emission peaks at 328/420 nm respectively, facilitates the quantification of SARS-CoV Mpros catalytic activity.
Molecular Weight:
1514.7
Formula:
C69H99N19O20.XCF3COOH
Target:
Others
T83719
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