AS2863619 is an oral inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19. Inhibition of CDK8/19 can enhance the activation of STAT5, thereby activating the Foxp3 gene. It can convert antigen-specific effector/memory T cells into Foxp3+ regulatory T cells to study various immune diseases.
Molecular Weight:
405.24
Purity:
99.40%
CAS Number:
[2241300-51-4]
Formula:
C16H14Cl2N8O
Target:
STAT|||CDK
T8378
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