DXR inhibitor 11a, with an IC50 value of 0.11 µM, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparums growth in isolated human erythrocytes, with an IC50 of 0.37 µM.
Molecular Weight:
279.2
Formula:
C10H11NO5P.Na
Target:
Others
T83885
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