IDR 1002, an innate defense regulator peptide, effectively diminishes bacterial load and mitigates inflammatory responses in murine models of sinusitis and acute bacterial lung infections. It suppresses LPS-induced activation of NF-kappaB and COX-2 while promoting the phosphorylation and activation of p38, ERK1/2, MSK1, and CREB.
Molecular Weight:
1652.06
CAS Number:
[1224095-25-3]
Formula:
C79H130N26O13
Target:
Integrin
T83942
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