ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ion signaling by directly targeting ITPR1. Furthermore, ARN 11391 amplifies calcium signaling in cells with mutant ITPR1 linked to SCA29, a variant of spinocerebellar ataxia.
Molecular Weight:
383.49
CAS Number:
[1214569-31-9]
Formula:
C22H29N3O3
Target:
Others|||Chloride channel
T83950
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