Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM).
Molecular Weight:
448.89
Purity:
0.9981
CAS Number:
[1029714-89-3]
Formula:
C23H18ClFN6O
Target:
c-Met/HGFR|||Apoptosis
T8416
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