Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are lipids influenced by dietary changes, playing a crucial role in insulin sensitivity. These compounds typically consist of a C-16 or C-18 fatty acid (for example, palmitoleic, palmitic, oleic, or stearic acid) linked to a hydroxy fatty acid with the same carbon chain length. 13-PAHSA, a derivative where palmitic acid is esterified to 13-hydroxy stearic acid, is notably prevalent in the adipose tissue of glucose-tolerant AG4OX mice, which exhibit enhanced glucose transport via the overexpression of the Glut4 glucose transporter. This observation, along with the metabolic benefits seen from other FAHFAs-including improved glucose tolerance, stimulated insulin secretion, and anti-inflammatory properties-suggests that 13-PAHSA may function as a bioactive lipid beneficial in managing metabolic syndrome and inflammation.
Molecular Weight:
538.9
CAS Number:
[2169306-42-5]
Formula:
C34H66O4
Target:
Others
T84407
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