MCHB-1, a potent agonist of the human cannabinoid 2 (CB2) receptor (EC50= 0.52 nM), demonstrates high selectivity for CB2 over CB1 (Kis = 3.7 and 110 nM, respectively), distinguishing itself from similar benzimidazole compounds that significantly alleviate peripheral pain while minimizing central nervous system side effects in mice.
Molecular Weight:
447.623
CAS Number:
[1046140-32-2]
Formula:
C28H37N3O2
Target:
Cannabinoid Receptor|||Others
T84442
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