2,3-dinor-8-iso Prostaglandin F2alpha, CAS [[221664-05-7]]

Product Overview

• Article Name: 2,3-dinor-8-iso Prostaglandin F2alpha, CAS [[221664-05-7]]
• Biozol Catalog Number: TGM-T84593
• Supplier Catalog Number: T84593
• Alternative Catalog Number: TGM-T84593-25UG, TGM-T84593-50UG, TGM-T84593-100UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: 2,3-dinor-iPF2alpha-III

Product Description

8-isoProstaglandin F2alpha (8-isoPGF2alpha, 8-isoprostane) is a byproduct of non-specific lipid peroxidation, resembling prostaglandin in structure. In humans and rats, its metabolite, 12,3-dinor-8-isoPGF2alpha, is formed following exogenous administration of 8-isoPGF2alpha, which is converted to 2,3-dinor-8-isoPGF1alpha and 2,3-dinor-8-isoPGF2alpha. Additionally, rat hepatocytes can further break down 8-isoPGF2alpha into a beta-oxidation product, 2,3,4,5-tetranor-8-isoPGF2alpha. The metabolite, 2,3-dinor-8-isoPGF2alpha, is normally found in human urine at concentrations of 200-300 pg/ml. Its levels rise in conditions associated with oxidative stress, such as smoking, demonstrating a correlation with the concentration of its precursor, 8-isoPGF2alpha.

Product Properties

• Molecular Weight: 326.4
• CAS Number: [221664-05-7]
• Formula: C18H30O5
• Target: Others|||Drug Metabolite