5-trans Prostaglandin D2, CAS [[2202725-84-4]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T84654
Supplier Catalog Number:
T84654
Alternative Catalog Number:
TGM-T84654-10MG,TGM-T84654-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Alternative Names:
5,6-trans PGD2
Prostaglandin D2 (PGD2) is one of the five principal prostaglandins enzymatically derived from PGH2. It is abundantly generated in the cerebrospinal fluid (CSF) by lipocalin-type PGD synthase and in peripheral regions by myeloid cells, such as mast cells and basophils, via leukocyte-type PGD synthase. The compound 1,25-trans-PGD2 is an isomer of PGD2, characterized by the alteration of the double bond between carbons 5 and 6 from cis(Z) to trans(E). This trans isomer, found as a 2-5% impurity in most commercial PGD2 bulk drug preparations, is primarily synthesized as an analytical standard to identify and quantify this impurity. Based on existing studies of trans isomers of F-type prostaglandins, 5-trans-PGD2 likely exhibits biological activity comparable to its cis isomer, although no specific published reports confirm this for 5-trans-PGD2.
Molecular Weight:
352.5
CAS Number:
[2202725-84-4]
Formula:
C20H32O5
Target:
Others
T84654
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