CL4F8-6, an ionizable cationic lipid with a pKa of 6.14, is utilized in lipid nanoparticles (LNPs) for mRNA therapeutics. When incorporated into LNPs delivering Cas9 mRNA and sgRNA, CL4F8-6 facilitates CRISPR-mediated gene knockdown in mice [1].
Molecular Weight:
808.35
CAS Number:
[2766493-12-1]
Formula:
C51H101NO5
Target:
Others|||Liposome
T84822
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